Relative Rates of Transcapillary Movement of Free Thyroxine, Protein-Bound Thyroxine, Thyroxine-Binding Proteins, and Albumin
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چکیده
منابع مشابه
Relative rates of transcapillary movement of free thyroxine, protein-bound thyroxine, thyroxine-binding proteins, and albumin.
The rate of appearance of labeled thyroxine (T4) and albumin in lymph from various areas after simultaneous i.v. injection of the labeled substances in conscious ambulatory sheep has been used to estimate the relative rates of transcapillary movement of stable T4 and albumin. Labeled T4 appeared in hepatic lymph at the same rate as albumin. In intestinal and leg lymph, labeled T4 appeared eight...
متن کاملEffective thyroxine ratio and free thyroxine index
Brien, T. G., Fay, J. A., and Griffin, E. A. (1974). Archives of Disease in Childhood, 49, 225. Thyroid status in the newborn infant: effective thyroxine ratio and free thyroxine index. The effective thyroxine ratio (ETR) was determined in 28 term and 17 premature infants at birth and in 17 infants aged 0 to 6 weeks. The mean values found were significantly higher than those in 20 adult euthyro...
متن کاملThyroxine-protein interactions. Interaction of thyroxine and triiodothyronine with human thyroxine-binding globulin.
The effect of temperature on the binding of thyroxine and triiodothyronine to thyroxine-binding globulin has been studied by equilibrium dialysis. Inclusion of ovalbumin in the dialysis mixture stabilized thyroxine-binding globulin against losses in binding activity which had been found to occur during equilibrium dialysis. Ovalbumin by itself bound the thyroid hormones very weakly and its bind...
متن کاملBinding of Thyroxine by Human Serum Albumin
In previous work from this laboratory (1) studies on equilibrium dialysis were carried out to determine the binding constants for the interaction of human serum albumin with thyroxine and its analogs. The classical technique of equilibrium dialysis as described by Scatchard and others (2-6) was employed. At present it seems clear that thyroxine in human serum migrates to at least three differen...
متن کاملThyroxine Binding by Human Serum Albumin*
Thyroxine and triiodothyronine are transported in the blood as noncovalent complexes with certain serum proteins. This has been shown by many investigators and was the subject of an extensive recent review by Robbins and Rall (1). The binding proteins are an a-globulin (called thyroxine-binding globulin), a prealbumin, and serum albumin. The first appears to be the most significant binder of th...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1974
ISSN: 0021-9738
DOI: 10.1172/jci107737